Learn more about a new PCDH19 mouse model used to study sleep disturbances, brain hyperexcitability, and epilepsy-like activity, presented at the 2018 PCDH19 Epilepsy Professional and Family Symposium. This session explores how targeted loss of PCDH19 in a mosaic pattern disrupts slow-wave sleep, alters neuronal communication, and reveals clues about seizure propagation and cognitive effects.
2018 PCDH19 Epilepsy Professional and Family Symposium
Disruption of The Excitation/Inhibition Equilibrium in The Conditional PCDH19 Mouse: Insights From in Vivo Electrophysiology
Dr. Gian Michele Ratto
Istituto Nanoscienze CNR and Scuola Normale
Pisa, Italy
Presented by the PCDH19 Alliance and the Department of Neurology UCSF School of Medicine
